最先端研究セミナー

講演者：　山崎　洋人（長岡技術科学大学　産学融合特任講師）

演題：　バイオセンシングとDNAシーケンシングのための半導体ナノポア技術の開発

日時： 2024年5月22日（水）12：00-13：00

Abstract:

Recent advancements in biotechnology have been remarkable in both the research and healthcare fields. These game-changing innovations have paved the way for breakthroughs in understanding complex biological systems, enabling personalized medicine, and accelerating drug discovery and development. Among these technologies, nanopore sequencer by oxford nanopore technologies become attractive technology because it offers portable long sequencing solution. This innovative approach employs protein nanopores embedded in a lipid membrane, where DNA strands are passed through, producing characteristic electrical signals that are decoded into nucleotide sequences. As a later development of protein nanopores, semiconductor based nanopore technologies emerged as a core-technology of next generation biosensor and DNA/RNA sequencing. In this talk, I will present the development history, basic and applications of nanopore technologies to provide a comprehensive understanding of nanopore technologies. This talk will consist of two parts: First part is developmental history of DNA sequencers by Oxford Nanopore technologies and beyond and second part is the overview of semiconductor based nanopore technologies including nanopore fabrication technology in semiconductor materials, detection of DNA, RNA, and protein, and my research works.

Reference:

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担当分野：　分子生理　富澤（内線：5050）